Integrity Optical Biosensor


The Biomagnetics Diagnosticís triggered optical biosensor is based on protein-receptor binding that brings two or more optically tagged receptors into close proximity using planar optical waveguides, thereby triggering fluorescence changes identified almost instantly by tiny on-board detectors. These devices are specifically designed to be battery operated and ultraportable, allowing for the rapid detection of various viral and bacterial pathogens by relatively untrained personnel outside of the laboratory setting.


Los Alamos originally developed the concept of a reagent-less, laser-based system for homeland security purposes, aiming to allow first responders to rapidly identify toxins and pathogens in the field. Broader applications, such as disease diagnostics, blood bank screening and hospital use, offer commercial partners an interesting opportunities.

Grace Report

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Video - Development of Rapid Diagnostics Using the Waveguide-based Optical Biosensor